HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1-aminocyclopropane-1-carboxylate hydrochloride → Methyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclopropanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1-aminocyclopropane-1-carboxylate hydrochloride | HCID 12760695 | — |
| Reactant | Methyl 4-(bromomethyl)-4'-nitrobiphenyl-3-carboxylate | HCID 67306641 | — |
| Reactant | (S)-Methyl 3-methyl-2-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)butanoate | HCID 131731440 | — |
| Product | Methyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclopropanecarboxylate | HCID 67313125 | 65% |
Reaction Steps
The compound of example 583 was prepared analogous to compound of example 5 by reaction of compound of example 4 with methyl 1-aminocyclopropanecarboxylate hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-20678c9ed6b149ce8a7af55ade3ca7f6 |
| Source note | uspto-grants-2014_06 |