HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzoyl chloride → Methyl 1-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopropane carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Reactant | Methyl 1-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclopropanecarboxylate | HCID 67313175 | — |
| Reactant | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| Product | Methyl 1-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopropane carboxylate | HCID 67306797 | 95% |
Reaction Steps
The compound of example 587 was prepared analogous to compound of example 97 by reaction of compound of example 584 with 4-chloro benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-049fcb184cc6469298fc064f7cabf865 |
| Source note | uspto-grants-2014_06 |