HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate → (1S,2R)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Reactant | (1S,2R)-Methyl 2-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylate | HCID 131731583 | — |
| Product | (1S,2R)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylate | HCID 131731584 | 90% |
Reaction Steps
The compound of example 592 was prepared analogous to the compound of example 6 by reduction of the compound of example 591.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-86b24cec5408433dbdac6185255b4976 |
| Source note | uspto-grants-2014_06 |