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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404080Generated: October 29, 2026

4-Chlorobenzoyl chloride → (1S,2R)-Methyl 2-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopentanecarboxylate

https://huagongshe.com/reaction/404080

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzoyl chlorideHCID 8501—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(1S,2R)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylateHCID 131731584—
Product(1S,2R)-Methyl 2-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopentanecarboxylateHCID 13173158595%

Reaction Steps

The compound of example 595 was prepared analogous to compound of example 97 by reaction of compound of example 592 with 4-chloro benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-9e1fde18a1e045cd92d0a0901a52fc3d
Source noteuspto-grants-2014_06