(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (1S,2R)-2-(6-(4-(4-Chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylic acid

Participants

Role	Name	HCID	Charge
Reactant	(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 53303631	—
Reactant	(1S,2R)-Methyl 2-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopentanecarboxylate	HCID 131731585	—
Product	(1S,2R)-2-(6-(4-(4-Chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclopentane carboxylic acid	HCID 67306793	82%

The compound of example 596 was prepared analogous to compound of example 98 by hydrolysis of compound of example 595.