(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(6-(4-(3-(4-Chlorophenyl)isoxazole-5-carboxamido)phenyl)-1-oxo isoindolin-2-yl)-3-methylbutanoic acid

Participants

Role	Name	HCID	Charge
Reactant	(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 53303631	—
Reactant	(S)-Methyl 2-(6-(4-(3-(4-chlorophenyl)isoxazole-5-carboxamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate	HCID 123822721	—
Product	(S)-2-(6-(4-(3-(4-Chlorophenyl)isoxazole-5-carboxamido)phenyl)-1-oxo isoindolin-2-yl)-3-methylbutanoic acid	HCID 67307123	94%

The compound of example 618 was prepared analogous to the compound of example 98 by hydrolysis of compound of example 617.