HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-3-Methyl-2-(6-(4-(4-(oxazol-5-yl)benzamido)phenyl)-1-oxoisoindolin-2-yl)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 53303631 | — |
| Reactant | HCID 131731590 | HCID 131731590 | — |
| Product | (S)-3-Methyl-2-(6-(4-(4-(oxazol-5-yl)benzamido)phenyl)-1-oxoisoindolin-2-yl)butanoic acid | HCID 67306148 | 73% |
Reaction Steps
The compound of example 622 was prepared analogous to the compound of example 98 by hydrolysis of compound of example 621.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-850fb83033974dc1bade28e1407742a3 |
| Source note | uspto-grants-2014_06 |