(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-3-Methyl-2-(6-(4-(5-methyl-2-phenyloxazole-4-carboxamido)phenyl)-1-oxoisoindolin-2-yl)butanoic acid

Participants

Role	Name	HCID	Charge
Reactant	(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 53303631	—
Reactant	(S)-Methyl 3-methyl-2-(6-(4-(5-methyl-2-phenyloxazole-4-carboxamido)phenyl)-1-oxoisoindolin-2-yl)butanoate	HCID 123480077	—
Product	(S)-3-Methyl-2-(6-(4-(5-methyl-2-phenyloxazole-4-carboxamido)phenyl)-1-oxoisoindolin-2-yl)butanoic acid	HCID 67306647	89%

The compound of example 643 was prepared analogous to the compound of example 98 by hydrolysis of compound of example 642.