HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid → (S)-Methyl 3-methyl-2-(6-(5-(5-methyl-2-phenyloxazole-4-carboxamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid | HCID 318533 | — |
| Reactant | (S)-Methyl 2-(6-(5-aminopyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731548 | — |
| Product | (S)-Methyl 3-methyl-2-(6-(5-(5-methyl-2-phenyloxazole-4-carboxamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)butanoate | HCID 123880489 | 64% |
Reaction Steps
The compound of example 654 was prepared analogous to the compound of example 640 by reaction of compound of example 392 with 5-methyl-2-phenyloxazole-4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-2f7fc71249f04b6e98d52c250be25103 |
| Source note | uspto-grants-2014_06 |