Hydroxylamine → HCID 46852450, compound

Participants

Reaction Steps

HONH2 (50% aqueous, 2 mL) was added to II (524 mg, 1.60 mmol) in DMF (0.5 mL) and MeOH (2 mL) at rt. The reaction mixture was stirred for 72 h, after which the solvents were evaporated under reduced pressure. The resulting residue was dissolved and co-evaporated with toluene (2×10 mL) then was purified by silica gel column chromatography eluting with CH2Cl2/MeOH (100:4 then 100:8) to furnish III as a colourless oil (425.79 mg, 85%).

Provenance & Evidence