Aluminium lithium hydride → HCID 58379883, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 4-(5-fluoro-2-methoxypyridin-4-yl)-3-(1-(methoxymethyl)cyclopentyl)benzoate (77.0 mg, 206 μmol) in THF (4.0 mL) was added LAH (0.42 mL, 1.0 M solution in diethyl ether, 412.0 μmol) at 0° C. The reaction mixture was stirred at 45° C. for 3 hours. After work up, the solvent was removed to provide the product which was used in the next step. MS ESI (pos.) m/e: 346.2 (M+H)+.

Provenance & Evidence