Thionyl Chloride → HCID 67361244, compound

Participants

Reaction Steps

To a room temperature solution of 29.5 (60 mg, 176 μmol) in DCM was added one drop of DMF followed by SOCl2(63 mg, 527 μmol). The mixture was stirred at room temperature for 2.0 hours. After removal of organic solvents under reduced pressure, purification of the residue by flash chromatography on silica gel with 0-5% MeOH/EtOAc provided 29.6 as a colorless oil (44 mg, 70%).

Provenance & Evidence