HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 45379226, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | N-(2-(dimethylamino)ethyl)-4-(3-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)ureido)-N-methylbenzamide | HCID 44516311 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 45379226 | HCID 45379226 | 88% |
Reaction Steps
To the N-(2-(dimethylamino)ethyl)-4-(3-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)ureido)-N-methylbenzamide (55 mg, 0.127 mmol) and MeOH (1 mL) was added 4N HCl in Dioxane (1 mL) and stirred for 3 hrs. The solid was filtered and washed with ether to give the product as a white solid (70 mg, yield=88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748421B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-cad234e013414a2194cabafba2c03097 |
| Source note | uspto-grants-2014_06 |