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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404476Generated: October 30, 2026

Trifluoroacetic acid → HCID 44546613, compound

https://huagongshe.com/reaction/404476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant2-MorpholinoethylamineHCID 408285—
ReactantHCID 44548798HCID 44548798—
ProductHCID 44546613HCID 44546613—

Reaction Steps

Starting from 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(4-oxopiperidin-1-yl)-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea.TFA (50 mg) and 1-(2-aminoethyl)morpholine (0.031 mL) and following the procedure as outlined in example 118, the titled compound was isolated as its tri-TFA salt after HPLC purification; MS (ES+) 615.9 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748421B2
Source datasetuspto-grants-2014_06
ORD IDord-07ffd94fd21142f6a1fd59d24086d72e
Source noteuspto-grants-2014_06