HRID404510

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11401617

Phenyl pyridin-4(1H)-ylidenecarbamate

C12H10N2O2

结构：CNC(=O)Nc1ccc(-c2nc(-c3ccc(N)cc3)nc(N3C(C)COCC3C)n2)cc1

HCID67438018

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)Nc1ccc(-c2nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc(N3C(C)COCC3C)n2)cc1

HCID66585611

未命名化合物

收率 0.8%

PROCEDURE

实验过程

The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-(3,5-dimethylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl pyridin-4-ylcarbamate. Yield 15 mg, 0.8% yield.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9073abb1f0dd4b41a7f1610c2318575d
来源数据集: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08748421B2
来源说明: uspto-grants-2014_06

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[C:12]([N:14]3[CH:19]([CH3:20])[CH2:18][O:17][CH2:16][CH:15]3[CH3:21])[N:11]=[C:10]([C:22]3[CH:27]=[CH:26][C:25]([NH:28][C:29]([NH:31][CH3:32])=[O:30])=[CH:24][CH:23]=3)[N:9]=2)=[CH:4][CH:3]=1.[N:33]1[CH:38]=[CH:37][C:36]([NH:39][C:40](=O)[O:41]C2C=CC=CC=2)=[CH:35][CH:34]=1>>[CH3:21][CH:15]1[CH2:16][O:17][CH2:18][CH:19]([CH3:20])[N:14]1[C:12]1[N:11]=[C:10]([C:22]2[CH:27]=[CH:26][C:25]([NH:28][C:29](=[O:30])[NH:31][CH3:32])=[CH:24][CH:23]=2)[N:9]=[C:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][C:40]([NH:39][C:36]3[CH:37]=[CH:38][N:33]=[CH:34][CH:35]=3)=[O:41])=[CH:7][CH:6]=2)[N:13]=1