HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine → 1-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine | HCID 224967 | — |
| Reactant | 3-Methyl-1-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea | HCID 17750273 | — |
| Product | 1-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 45379222 | 11% |
Reaction Steps
The title compound was prepared by following the procedure of example 473 step 2 using 4,4′-(6-chloro-1,3,5-triazine-2,4-diyl)dimorpholine and 1-Methyl-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-urea. Yield 13 mg, 11% yield; HPLC: Rt=1.98 min; MS 400 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748421B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a37e03f0659048b596e7fa6961f04cf5 |
| Source note | uspto-grants-2014_06 |