Phosphorus pentachloride → HCID 71463896, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-O-acetyl-11-keto-β-boswellic acid (5 g, 0.0097 mol), 3 mL of chloroform taken in a round bottom flask. Then phosphorous pentachloride (16 g; 0.078 mol) was added to reaction mixture (RM) at Room temperature. RM was stirred at 50° C. for 1 hr, then stirred at RT for 4 hours. Then RM was poured in ice cold water, extracted with Ethyl acetate (EtOAc), organic layer was washed with brine, dried over sodium sulphate and concentrated. The crude was subjected to column chromatography, hexane/acetone as an eluent. Compound eluted in 15% acetone in hexane. [Yield 2 g; Percentage of yield is 39.2%].

Provenance & Evidence