Oxalate → HCID 44427818, compound

Participants

Role	Name	HCID	Charge
Reactant	Oxalate	HCID 71081	—
Reactant	1-(4-Aminobutyl)-4-(2-methoxyphenyl)piperazine	HCID 10999903	—
Reactant	4-(2-Pyridyl)benzoic acid hydrochloride	HCID 68499643	—
Product	HCID 44427818	HCID 44427818	53%

Reaction Steps

Prepared from 4-pyridin-2-yl-benzoic acid hydrochloride and 4-(4-(2-methoxy-phenyl)-piperazin-1-yl)-butylamine according to the general procedure. Yield: 53%. Mp. (oxalate): foam. 1H NMR (CDCl3): δ1.67-1.74 (m, 4H), 2.49 (t, J 6.84, 2H), 2.67 (s, 2H), 3.07 (s, 2H), 3.51 (q, J 6.0, 2H), 3.84 (s, 3H), 6.83 (m, 5H), 7.26 (m, 1H), 7.73-7.79 (m, 2H), 7.89 (d, J 8.2, 2H), 8.06 (d, J 8.6, 2H), 8.71 (dt, J 4.7, 1.3, 1H). 13C NMR (CDCl3): δ 24.8, 27.9, 40.4, 50.8, 53.9, 55.8, 58.5, 111.6, 118.7, 121.3, 121.4, 128.1, 123.4, 127.4, 127.9, 135.6, 137.3, 142.5, 150.3, 152.7, 156.7, 167.8. Anal. (C27H32N4O2.(COOH)2.0.75H2O) C, H, N.|

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08748608B2
Source dataset	uspto-grants-2014_06
ORD ID	ord-2fc03e2ec67e4cb5a945b6f861544e2b
Source note	uspto-grants-2014_06