Phenylboronic Acid → HCID 59540290, compound

Participants

Reaction Steps

A mixture of phenylboronic acid (400 mg, 3.28 mmol), 4,4-difluoropiperidine (397 mg, 3.28 mmol) and 2-oxoacetic acid hydrate (302 mg, 3.28 mmol) in DCM (30 ml) was stirred at room temperature overnight. DCM was evaporated and crude was purified by flash-chromatography (DCM/MeOH=8/2) to obtain the title compound (512 mg, 61.1% yield) as a white solid.

Provenance & Evidence