Azepane → HCID 20992498, compound

Participants

Reaction Steps

A mixture of phenylboronic acid (400 mg, 3.28 mmol), azepane (0.37 ml, 3.28 mmol) and 2-oxoacetic acid hydrate (302 mg, 3.28 mmol) dissolved in DCM (30 ml) was stirred at room temperature overnight. DCM was removed under vacuum and the crude was purified by flash chromatography (DCM/MeOH=8/2) to obtain the title compound (476 mg, 62.2% yield) as a white solid.

Provenance & Evidence