Diethyl Ether → HCID 86688920, compound

Participants

Reaction Steps

2-Chloro-1-phenylethanone (46.9 mg, 0.30 mmol) was added to a solution of (R)-quinuclidin-3-yl 2-(azepan-1-yl)-2-phenylacetate (104 mg, 0.30 mmol) in ethyl acetate (3 ml). The reaction was stirred at room temperature overnight then Et2O (2 mL) was added, the suspension was sonicated, filtered and dried under vacuum at 40° C. overnight to obtain the title compound (99 mg, 65.6% yield) as a white solid.

Provenance & Evidence