HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromoisoquinoline → 7-Chloro-6-fluoroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromoisoquinoline | HCID 313681 | — |
| Reactant | 3-Chloro-4-fluorobenzaldehyde | HCID 593866 | — |
| Product | 7-Chloro-6-fluoroisoquinoline | HCID 53418922 | — |
Reaction Steps
Starting from 4-Fluoro-3-chlorobenzaldehyde, the title compound was synthesized by the protocol described for 6-Bromo-isoquinoline (3). Rt=0.77 min (Method A). Detected mass: 182.1/184.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748614B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-1d0e5402af254e49bee4226bfb92c36d |
| Source note | uspto-grants-2014_06 |