HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68592103, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-Bromo-7-chloroisoquinoline | HCID 53418615 | — |
| Reactant | HCID 68590720 | HCID 68590720 | — |
| Product | HCID 68592103 | HCID 68592103 | — |
Reaction Steps
Starting from 6-Fluoro-7-chloroisoquinoline (263) and 3-Bromomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 7-Chloro-6-(pyrrolidin-3-ylmethylsulfanyl)-isoquinoline could be obtained according to the procedures described for 272, 267, 268 as the hydrochloride. Rt=0.87 min (Method B). Detected mass: 279.1/281.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748614B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-272a51d223e24496ba21df79007ecac4 |
| Source note | uspto-grants-2014_06 |