HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-5-nitroaniline → N-(5-amino-2-methoxyphenyl)-N'-(3-chloro-4-fluorophenyl)pyrimidine-4,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-5-nitroaniline | HCID 7447 | — |
| Reactant | 4-(3-Chloro-4-fluorophenylamino)-6-chloropyrimidine | HCID 54258656 | — |
| Product | N-(5-amino-2-methoxyphenyl)-N'-(3-chloro-4-fluorophenyl)pyrimidine-4,6-diamine | HCID 58434677 | — |
Reaction Steps
In a manner substantially similar to that described above 4-(3-chloro-4-fluorophenylamino)-6-chloropyrimidine and 2-methoxy-5-nitroaniline gave N-(5-amino-2-methoxyphenyl)-N′-(3-chloro-4-fluorophenyl)pyrimidine-4,6-diamine. (Int-G) MS (m/z): 360/362 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748606B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-c47b93d9446f4799b52455019d877f65 |
| Source note | uspto-grants-2014_06 |