HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → n-Hydroxy-4-(4-isopropoxyphenoxy)benzenecarboximidoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 4-(4-Isopropoxyphenoxy)benzaldehyde oxime | HCID 131731604 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | n-Hydroxy-4-(4-isopropoxyphenoxy)benzenecarboximidoyl chloride | HCID 131731605 | 104.2% |
Reaction Steps
To a solution of Example 17C (1.48 g, 5.56 mmol) in N,N-dimethyl formamide (15 mL) was added N-chlorosuccinimide (0.70 g, 5.24 mmol) at room temperature. The mixture was stirred at room temperature overnight. The mixture was poured into water. The aqueous layer was extracted with ether washed with water, then brine, and dried over MgSO4 and concentrated to give the title compound as an oil (1.67 g, 100%),
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748627B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-4445b2fac22d455bbc5e5c64ace595d9 |
| Source note | uspto-grants-2014_06 |