Hydrazine hydrate (1:1) → HCID 69435781, compound

Participants

Reaction Steps

To a solution of Example 17E (168 g, 3.59 mmol) in dichloromethane (25 ml) and ethanol (2.5 mL) was added hydrazine monohydrate (100 mL, 20.6 mmol). The mixture was stirred at room temperature overnight. The reaction was filtered and the filtrate concentrated. The residue was dissolved in dichloromethane again and filtered. The filtrate was concentrated to give the amine as a colorless oil (1.20 g, theory: 100%).

Provenance & Evidence