Dimethylamine → HCID 86762478, compound

HRID 404995Notes

Reaction equation

HRID 404995 reaction equation
[CH3:1][NH:2][CH3:3].[C:4]([OH:9])(=[O:8])[C:5]([CH3:7])=[CH2:6]>>[CH3:1][NH:2][CH3:3].[C:4]([OH:9])(=[O:8])[C:5]([CH3:7])=[CH2:6]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 4093Methacrylic Acid3×

Product 1

HCID 86762478HCID 86762478, compound

Procedure

Dimethylamine (30 g) was added to a pressure-resistant container (reactor), and the reactor was hermetically sealed. The temperature of the reactor was adjusted to 20° C., and methacrylic acid (14.3 g) was fed into the reactor by means of a high-pressure pump. During addition of methacrylic acid, heat of neutralization is generated. Therefore, while the reactor was cooled in an ice bath, methacrylic acid was added dropwise to the reactor at a rate of 5 to 7 mL/minute, so as to adjust the temperature in the reactor to 25 to 35° C. After completion of dropwise addition, reaction was allowed to proceed for one hour, and then analysis was carried out. The reaction time (as measured from initiation of dropwise addition) was one hour and three minutes.

Workup

  1. customthe reactor was hermetically sealed
  2. customwas adjusted to 20° C.
  3. temperatureheat of neutralization
  4. temperatureTherefore, while the reactor was cooled in an ice bath
  5. customto 25 to 35° C
  6. additionAfter completion of dropwise addition, reaction
  7. additionThe reaction time (as measured from initiation of dropwise addition)
  8. waitwas one hour and three minutes

Sources & evidence

ORD record
ord-d3c906adec724197b7b06cdc0b2e17fa
Source dataset
uspto-grants-2014_06
Patent number
US08748659B2

Reaction notes

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