HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 405187Generated: October 30, 2026
1-bromo-3-chloro-2-iodo-5-(trifluoromethyl)benzene → HCID 71060016, compound
https://huagongshe.com/reaction/405187
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-bromo-3-chloro-2-iodo-5-(trifluoromethyl)benzene | HCID 2736230 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71060016 | HCID 71060016 | — |
Reaction Steps
1-bromo-3-chloro-2-iodo-5-(trifluoromethyl)benzene (8.0 g, 20.6 mmol) and CuCN (1.9 g, 20.6 mmol) were dissolved in DMF (20 mL) and heated 100° C. After 2 h the temperature was increased to 110° C. After 3 h the reaction was cooled to room temperature, diluted with DCM, filtered, concentrated, and purified via column chromatography to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08748624B2 |
|---|
| Source dataset | uspto-grants-2014_06 |
|---|
| ORD ID | ord-8519e4132f5d4c42ad1b5d85a7a51385 |
|---|
| Source note | uspto-grants-2014_06 |
|---|
