HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40520Generated: October 25, 2026
N-((1S)-1-(4-Bromophenyl)ethyl)acetamide → (S)-N-(1-{4-[3-(4-Benzyloxy-phenoxy)-azetidin-1-yl]-phenyl}-ethyl)-acetamide
https://huagongshe.com/reaction/40520
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-((1S)-1-(4-Bromophenyl)ethyl)acetamide | HCID 793484 | — |
| Reactant | 3-[4-(Benzyloxy)phenoxy]azetidine | HCID 53409556 | — |
| Product | (S)-N-(1-{4-[3-(4-Benzyloxy-phenoxy)-azetidin-1-yl]-phenyl}-ethyl)-acetamide | HCID 86689007 | — |
Reaction Steps
Example 8.5 is prepared analogously to 8.1. 3-(4-Benzyloxy-phenoxy)-azetidine and (S)—N-[1-(4-bromo-phenyl)-ethyl]-acetamide (I.1) are used as starting materials. Reaction conditions are stirring for 2 days at 30° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08530461B2 |
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| Source dataset | uspto-grants-2013_09 |
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| ORD ID | ord-28757e03b49a4eccbe90e35c5a61a548 |
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| Source note | uspto-grants-2013_09 |
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