Ammonium formate → HCID 71059930, compound

Participants

Reaction Steps

A mixture of 3-(5-(2-(((4′-fluoro-[1,1′-biphenyl]-4-yl)amino)methyl)-5-(prop-1-en-2-yl)phenyl)picolinamido)propanoic acid (46 mg, 0.09 mmol), ammonium formate (57 mg, 0.91 mmol) and 10% Pd—C (10 mg, 0.01 mmol) in MeOH (5 mL) was refluxed. After 1 h, the resulting mixture was filtered through celite and washed with DCM-MeOH. The filtrate was concentrated and purified via column chromatography to yield the title compound.

Provenance & Evidence