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4-Bromoaniline → 2'-Chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromoaniline | HCID 7807 | — |
| 反応物 | 4-Bromo-3-chloroaniline | HCID 88888 | — |
| 反応物 | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| 反応物 | [2-Chloro-4-(trifluoromethyl)phenyl]boronic acid | HCID 2783251 | — |
| 生成物 | 2'-Chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine | HCID 69133514 | — |
反応手順
The title compound was prepared as described in Example 159 substituting 4-bromoaniline and (2-chloro-4-(trifluoromethyl)phenyl)boronic acid for 4-bromo-3-chloroaniline and (4-(trifluoromethyl)phenyl)boronic acid, respectively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08748624B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-b979d84848004730af0e81e1951fc5aa |
| 出典メモ | uspto-grants-2014_06 |