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HRID405445

反应详情

EQUATION

反应方程式

HRID 405445 的结构方程式

REACTANTS

反应物

3
结构：Cc1noc(C)c1N
HCID182040

3,5-Dimethyl-1,2-oxazol-4-amine

C5H8N2O

结构：Oc1cccc(Nc2ncc(F)c(Nc3ccc4c(c3)OCCO4)n2)c1
HCID22060334

未命名化合物

结构：Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2
HCID22060362

未命名化合物

PRODUCTS

生成物

1
结构：Cc1noc(C)c1Nc1ncc(F)c(Nc2ccc3c(c2)OCCO3)n1
HCID22060831

未命名化合物

PROCEDURE

实验过程

In a manner similar to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, 2-chloro-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine and 3,5-dimethyl-4-isoxazolamine were reacted to yield N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3,5-dimethylisoxazol-4-yl)-2,4-pyrimidinediamine. LCMS: ret. time: 18.89 min.; purity: 98%; MS (m/e): 358 (MH+).

WORKUP

后处理

  1. customwere reacted