Diethyl Ether → Mad heaa

Participants

Reaction Conditions

Reaction Steps

In 60.0 g of methanol were dissolved 19.14 g (67.63 mmol) of 12-methacrylamidododecanoic acid (MAD), 0.86 g (7.51 mmol) of N-hydroxyethylacrylamide (HEAA: Kohjin Co., Ltd.), and 0.33 g (1.97 mmol) of azobisisobutyronitrile (Nacalai Tesque, Inc.). Before use, azobisisobutyronitrile was recrystallized from methanol in the usual way. The solution was deaerated by bubbling argon for 60 minutes. The container was covered with a septum, and the polymerization was conducted by heating at 60° C. for 20 hours. After the completion of the polymerization reaction, the reaction solution was dropwise added into a large excess of diethyl ether, and the resulting precipitate was collected by filtration under suction. After drying under reduced pressure, 16.90 g of MAD/HEAA copolymer (90/10) was obtained (yield: 84.5%).

Provenance & Evidence