HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 5-(Tert-butyl)-2-chloropyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5-(tert-butyl)pyrimidin-2(1H)-one | HCID 14943594 | — |
| Product | 5-(Tert-butyl)-2-chloropyrimidine | HCID 14943595 | — |
Reaction Steps
200 mL POCl3 and 14 g (0.09 mol) 5-tert-butylpyrimidin-2(1H)-one are heated in a sealed glass ampoule for 3 h at 160° C. The mixture is cooled and the excess
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530460B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-e6544b0204d542119421404452d51507 |
| Source note | uspto-grants-2013_09 |