HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 2-Pyridinecarboxylicacid,5-(2,2,3,3-tetrafluoropropoxy)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | 5-(2,2,3,3-Tetrafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester | HCID 57475874 | — |
| Product | 2-Pyridinecarboxylicacid,5-(2,2,3,3-tetrafluoropropoxy)- | HCID 57475855 | 94% |
Reaction Steps
In a manner analogous to that described in example 17b), the hydrolysis of the 5-(2,2,3,3-tetrafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester with lithium hydroxide yielded the title compound as a light yellow solid (yield 94% of theory). MS (ISP): m/z=253 [M]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754075B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-5b69fdd955ca4479964f3f12f567d041 |
| Source note | uspto-grants-2014_06 |