HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarboxylic acid → HCID 66558859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarboxylic acid | HCID 15655 | — |
| Reactant | (4R,5R)-4-(5-amino-2-fluoro-phenyl)-5-fluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine | HCID 86672004 | — |
| Product | HCID 66558859 | HCID 66558859 | — |
Reaction Steps
The condensation of (4R,5R)-4-(5-amino-2-fluoro-phenyl)-5-fluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate A8.2) and cyclopropanecarboxylic acid following procedure I yielded the title compound as a white foam. MS (ISP): m/z=310.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754075B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a613c69607e94eb3850595a90655b21b |
| Source note | uspto-grants-2014_06 |