HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → N-hydroxy-6-methyl-pyridine-2-carboxamidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 6-Methylpyridine-2-carbonitrile | HCID 74182 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-hydroxy-6-methyl-pyridine-2-carboxamidine | HCID 136295641 | — |
Reaction Steps
6-Methylpicolinonitrile (12 mg, 0.1 mmol) was dissolved in EtOH (0.5 mL) and treated with NH2OH (1.5 eq of a 50% aq solution). The mixture was stirred at room temperature for 12 hours then reduced to dryness to afford N′-hydroxy-6-methylpicolinimidamide (6) as a clear yellow oil, which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754071B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-cda047e0ea6d438c932ab5e0b5713c40 |
| Source note | uspto-grants-2014_06 |