HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthalenecarboxaldehyde → 4-Naphthalen-2-ylmethyl-piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthalenecarboxaldehyde | HCID 6201 | — |
| Reactant | N-(4-Fluorophenyl)piperazine-1-carboxamide | HCID 16228149 | — |
| Product | 4-Naphthalen-2-ylmethyl-piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide | HCID 11660560 | — |
Reaction Steps
The title compound was prepared from piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide and 2-naphthalenecarbaldehyde. 1H NMR (400 MHz, CDCl3): 7.85-7.80 (m, 3H), 7.74 (s, 1H), 7.52-7.45 (m, 3H), 7.30-7.25 (m, 2H), 6.98-6.92 (m, 2H), 6.36 (s, 1H), 3.69 (s, 2H), 3.49 (t, J=5.1 Hz, 4H), 2.51 (t, J=5.1 Hz, 4H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530476B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-cf79d09ed26a44159cfafe9c96e97034 |
| Source note | uspto-grants-2013_09 |