2-Amino-4-fluorophenol → HCID 58117545, compound

HRID 405925Notes

Reaction equation

HRID 405925 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[OH:9].[CH3:10][C:11]1([C:24]([O-])=O)[CH2:16][CH2:15][N:14](C(OC(C)(C)C)=O)[CH2:13][CH2:12]1>>[F:8][C:6]1[CH:5]=[CH:4][C:3]2[O:9][C:10]([C:11]3([CH3:24])[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]3)=[N:1][C:2]=2[CH:7]=1

Participants

3

Reactant 2

HCID 27359172-Amino-4-fluorophenolHCID 40419056HCID 40419056, compound

Product 1

HCID 58117545HCID 58117545, compound

Procedure

Starting from 2-amino-4-fluorophenol and mono-tert-butyl 4-methylpiperidine-1,4-dicarboxylate (V-9) may be prepared and purified analogously to (V-8) (see 45.1).

Workup

  1. custommay be prepared
  2. custompurified analogously to (V-8) (see 45.1)

Sources & evidence

ORD record
ord-8cf542bd8c5042b2bf8d0ffe011bcdd5
Source dataset
uspto-grants-2014_06
Patent number
US08754073B2

Reaction notes

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