2,4-Difluoronitrobenzene → HCID 178486053, compound

HRID 406011Notes

Reaction equation

HRID 406011 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12]([O:16][C:17](=[O:27])[N:18]([C@H:20]1[CH2:25][CH2:24][C@H:23]([OH:26])[CH2:22][CH2:21]1)[CH3:19])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:27])[N:18]([C@H:20]1[CH2:21][CH2:22][C@H:23]([O:26][C:2]2[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=2[N+:9]([O-:11])=[O:10])[CH2:24][CH2:25]1)[CH3:19])([CH3:15])([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 178486055HCID 178486055, compound

Product 1

HCID 178486053HCID 178486053, compound

Procedure

Prepared analogously to example III.1 from 1.11 ml 2,4-difluoronitrobenzene and 1.56 g trans-(4-hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester.

Sources & evidence

ORD record
ord-fb17fc1fc7574e1685dfc15e304ee0a8
Source dataset
uspto-grants-2014_06
Patent number
US08754079B2

Reaction notes

Loading…