Methanesulfonyl chloride → HCID 178484840, compound

HRID 406015Notes

Reaction equation

HRID 406015 reaction equation
Cl.[F:2][C:3]1[CH:4]=[CH:5][C:6]([N+:18]([O-:20])=[O:19])=[C:7]([CH:17]=1)[O:8][C@@H:9]1[CH2:14][CH2:13][C@H:12]([NH:15][CH3:16])[CH2:11][CH2:10]1.[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[F:2][C:3]1[CH:4]=[CH:5][C:6]([N+:18]([O-:20])=[O:19])=[C:7]([CH:17]=1)[O:8][C@@H:9]1[CH2:14][CH2:13][C@H:12]([N:15]([CH3:16])[S:22]([CH3:21])(=[O:24])=[O:23])[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 178484838HCID 178484838, compound

Product 1

HCID 178484840HCID 178484840, compound

Procedure

Prepared analogously to example IV.3 from 0.252 g [cis-4-(5-fluoro-2-nitro-phenoxy)cyclohexyl]-methyl-amine hydrochloride and methanesulfonyl chloride.

Sources & evidence

ORD record
ord-f23bd300f6fa44b5bdaf80dba71b06d4
Source dataset
uspto-grants-2014_06
Patent number
US08754079B2

Reaction notes

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