HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 67390935, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 67390398 | HCID 67390398 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67390935 | HCID 67390935 | — |
Reaction Steps
Prepared analogously to example 1.4 from 0.1 g racemic 4-[2-((cis)-3-methoxycyclohexyloxy)-pyridin-3-ylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid and ammonia (7 M in methanol) using TBTU instead of HATU in DMF as solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754079B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-1e7362f2c5a94b25bbfae842c0e846a9 |
| Source note | uspto-grants-2014_06 |