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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406085Generated: October 30, 2026

Ammonia → HCID 67390497, compound

https://huagongshe.com/reaction/406085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
ReactantHCID 67390796HCID 67390796—
SolventDimethylformamideHCID 6228—
ProductHCID 67390497HCID 67390497—

Reaction Steps

Prepared analogously to example 1.4 from 0.11 g racemic 4-[2-((trans)-3-Methoxycyclohexyloxy)-pyridin-3-ylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid and ammonia (7 M in methanol) using TBTU instead of HATU in DMF as solvent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754079B2
Source datasetuspto-grants-2014_06
ORD IDord-91ce7315d3d04576974df3244713b872
Source noteuspto-grants-2014_06