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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406093Generated: October 30, 2026

N,N-Dimethyl-1,3-propanediamine → HCID 178429337, compound

https://huagongshe.com/reaction/406093

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethyl-1,3-propanediamineHCID 7993—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
ReactantHCID 178429621HCID 178429621—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178429337HCID 178429337—

Reaction Steps

Prepared analogously to 1.4 from 0.083 g 4-[2-(trans-4-hydroxy-cyclohexyloxy)pyridin-3-ylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid and 26 μl N,N-dimethyl-1,3-propanediamine in THF using TBTU instead of HATU.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754079B2
Source datasetuspto-grants-2014_06
ORD IDord-b4dc7b57c3584e6d845316ad63334f08
Source noteuspto-grants-2014_06