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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406122Generated: October 31, 2026

Benzeneacetic acid, 4-bromo- → HCID 67479678, compound

https://huagongshe.com/reaction/406122

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 4-bromo-HCID 74654—
Reactant4-AminotetrahydropyranHCID 419223—
ProductHCID 67479678HCID 67479678100%

Reaction Steps

The title compound was prepared in substantially the same way as intermediate (iv) by coupling of tetrahydropyran-4-yl amine with (4-bromo-phenyl)-acetic acid to give 0.65 g (100% yield) as a thick oil which solidified on standing.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754095B2
Source datasetuspto-grants-2014_06
ORD IDord-00d8476672d546e589490e539c50c498
Source noteuspto-grants-2014_06