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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406186Generated: October 30, 2026

Ethyl 5-bromovalerate → 5-(2,3-Diphenyl-7,8-dihydropyrido[3,2-b]pyrazin-5(6H)-yl)pentanoic acid

https://huagongshe.com/reaction/406186

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-bromovalerateHCID 84580—
Reactant2,3-Diphenyl-5,6,7,8-tetrahydropyrido[3,2-b]pyrazineHCID 66665561—
Product5-(2,3-Diphenyl-7,8-dihydropyrido[3,2-b]pyrazin-5(6H)-yl)pentanoic acidHCID 66665610—

Reaction Steps

This compound was prepared from 2,3-diphenyl-5,6,7,8-tetrahydropyrido[3,2-b]pyrazine (Example 4.1 step 1) and ethyl 5-bromovalerate analogously to 7-(6,7-diphenyl-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)heptanoic acid (Example 1 step 1 and step 2. Step 1 was carried out using microwave radiation).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754085B2
Source datasetuspto-grants-2014_06
ORD IDord-1dcf00b9ef984f348c5ce58c19fa1fbb
Source noteuspto-grants-2014_06