6-Bromo-2-tetralone → HCID 57880869, compound

HRID 40623Notes

Reaction equation

HRID 40623 reaction equation
[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[CH2:23][C:22](=O)[CH2:21][CH2:20]2>>[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][N:13]([CH:22]3[CH2:21][CH2:20][C:19]4[C:24](=[CH:25][CH:26]=[C:17]([Br:16])[CH:18]=4)[CH2:23]3)[CH2:12][CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 27335536-Bromo-2-tetraloneHCID 7015289N-phenylpiperazine-1-carboxamide

Product 1

HCID 57880869HCID 57880869, compound

Procedure

The title compound was prepared from piperazine-1-carboxylic acid phenylamide and 6-bromo-3,4-dihydro-1H-naphthalen-2-one. 1H NMR (400 MHz, CDCl3): 7.37-7.21 (m, 6H), 7.06-7.02 (m, 1H), 6.96-6.94 (m, 1H), 6.33 (s, 1H), 3.55-3.53 (m, 4H), 2.94-2.64 (m, 9H), 2.12-2.08 (m, 1H), 1.69-1.61 (m, 1H).

Sources & evidence

ORD record
ord-64f5cbd7c0d24b499e404b69f1c2aa9c
Source dataset
uspto-grants-2013_09
Patent number
US08530476B2

Reaction notes

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