Diethyl Ether → HCID 178505901, compound

Participants

Reaction Steps

trans-3-{[4-Fluoro-3-(trifluoromethyl)phenyl]oxy}-N-(imidazo[1,2-a]pyridin-8-ylmethyl)cyclobutanamine (1035 mg, 2.73 mmol) and maleic acid (317 mg, 2.73 mmol) were dissolved in methanol (20 mL) and the solution stirred for 30 minutes. It was then concentrated in vacuo to give an orange gum. Diethyl ether was added to this residue to precipitate out the salt as a solid. The ether was removed in vacuo to give the title compound as a pale orange solid (1.299 g, 2.62 mmol).

Provenance & Evidence