N-bromobutanimide → 2-Bromomethyl-4-tert-butyl-1-methoxybenzene

Participants

Reaction Steps

N-Bromosuccinimide (5.66 g) and 2,2′-azobis(isobutyronitrile) (71 mg) were added to a solution of 4-tert-butyl-1-methoxy-2-methylbenzene (5.16 g) in carbon tetrachloride (25 mL), and the mixture was heated under reflux for 1.5 hours. The reaction solution was ice-cooled and then the insoluble matter was removed by filtration. The filtrate was concentrated under reduced pressure to obtain 7.78 g of the title compound. The property values of the compound are as follows.

Provenance & Evidence