benzyl N'-[3-methoxy-4-(4-methylimidazol-1-yl)benzoyl]hydrazinecarboxylate → 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzohydrazide

Participants

Reaction Steps

To a solution of benzyl N′-[3-methoxy-4-(4-methylimidazol-1-yl)benzoyl]hydrazinecarboxylate (1.25 g) in methanol (60 mL) was added 20% palladium hydroxide-carbon (50% wet, 250 mg) and the mixture was hydrogenated at an intermediate pressure (3.8 atm) for two hours and 30 minutes. The palladium-carbon was removed by filtration through celite. The filtrate was concentrated under reduced pressure to obtain 826 mg of the title compound. The property values of the compound are as follows.

Provenance & Evidence